Medicine Information

How To Medically Treat Nail Fungus


Warning: This article is for information only and can not be used to supplement your doctor's advice. You should contact your doctor for nail fungus treatment.

Treatment Of Toe Nail Fungus

Medical Care:

Several years ago the medical management of OM was limited to topical therapy and 2 unreliable systemic drugs: griseofulvin and ketoconazole. Topical therapy is beneficial only for mild cases involving the very distal nail plate. The use of griseofulvin and ketoconazole is plagued by high relapse rates (70-85%), prolonged treatment regimens (10-18 mo for toenails), constant laboratory monitoring, and numerous adverse effects. The introduction of newer oral agents has revolutionized the medical treatment of OM and reduced potential adverse effects and drug interactions. As the rate of recurrence remains high, even with newer agents, the decision to treat should be made with a clear understanding of the cost and risks involved as well as the risk of recurrence..

Topical antifungals

The use of topical agents should be limited to cases involving less than half of the distal nail plate or for patients unable to tolerate systemic treatment. Agents include amorolfine (approved in other countries), ciclopirox olamine 8% nail lacquer solution, sodium pyrithione, bifonazole/urea (available outside the United States), propylene glycol-urea-lactic acid, the imidazoles, and the allylamines.

Topical treatments alone are generally unable to cure OM because of insufficient nail plate penetration. Ciclopirox solution has been reported to penetrate through all nail layers but has low efficacy when used as monotherapy. It may be useful as adjunctive therapy in combination with oral therapy or as prophylaxis to prevent recurrence in patients cured with systemic agents.

Oral therapy

The newer generation of oral antifungal agents (itraconazole and terbinafine) has replaced older therapies in the treatment of nail fungus. They offer shorter treatment regimens, higher cure rates, and fewer adverse effects. Fluconazole (not approved by the Food and Drug Administration [FDA] for treatment of nail fungus) offers an alternative to itraconazole and terbinafine. Derivatives of fluconazole may also be available soon. The efficacy of the newer antifungal agents lies in their ability to penetrate the nail plate within days of starting therapy. Recent evidence shows better efficacy with terbinafine than other oral agents.

To decrease the adverse effects and duration of oral therapy, topical and surgical treatments may be combined with oral antifungal management.

Surgical Care:

Surgical approaches to nail fungus treatment include surgical nail avulsion and matrixectomy by chemical or mechanical means. Chemical removal by using a 40-50% urea compound should be reserved for patients with very thick nails or for those who may not tolerate mechanical avulsion.

Removal of the nail plate should be considered an adjunctive treatment in patients undergoing oral therapy.

A combination of oral, topical, and surgical therapy can increase efficacy and reduce cost.

Activity: Activity does not need to be limited during treatment, but patients should be educated about avoiding direct contact with high-risk areas in public places.

Gregory Mburu is a medical professional and a marketer part time. He post info about nail fungus on his blog at http://nail-fungus-cure.blogspot.com


MORE RESOURCES:
This RSS feed URL is deprecated, please update. New URLs can be found in the footers at https://news.google.com/news


CNET

Driving on cold medicine could get you locked up in the UK
CNET
Wouldn't it be kind of weird if you got pulled over while driving and the police officer, in their mirrored shades walks up to your open window and asks you in a grave tone, "Have you had any cold medicine today? I'm going to need you step out of the ...



Health24

Is integrative medicine right for you?
Health24
Any approach that differs from conventional – or Western – medicine is typically considered complementary and alternative, or CAM. But these practices have become much more mainstream, leading to growth in the healthcare approach called integrative ...



The Columbus Dispatch

Camp gives students a real-world taste of a career in medicine
The Columbus Dispatch
Inshira Dartey has long considered a career in health care, so he was excited to participate in a four-day summer camp for high school students put on by Ohio University's Heritage College of Osteopathic Medicine at Dublin. But Inshira, a rising junior ...



Feedstuffs

Efforts made to use antibioitics judiciously in human medicine
Feedstuffs
I recently got an up-close and personal tutelage on what's new since I left the field of medicine and went into public health. My 69-year-old wife of 47 years was suffering from rigors (severe shaking often associated with fevers) but had a normal ...



Turning food into medicine
HeraldLIVE
While diabetes cannot be “cured” it can be sent into remission by a healthy diet. This is just one example of food-as-medicine, a subject that has interested me for almost as long as I've been cooking professionally (almost 60 years) and one that is ...



New Scientist

Cannabis oil: what is it and does it really work as medicine? | New ...
New Scientist
The UK government is reviewing medicinal cannabis after two boys with severe epilepsy were withheld cannabis oil treatments. Here's everything you need to ...
British drug to be first ever cannabis epilepsy medicine to gain ...Telegraph.co.uk

all 9 news articles »


Chicago Daily Herald

Northwestern Medicine neurosurgeon describes medical mission to India as transformative
Chicago Daily Herald
Sheri Dewan, MD, a neurosurgeon from Lake Forest, Ill., experienced the global health crisis firsthand on a recent humanitarian medical mission to southern India. Dr. Dewan, who practices at Northwestern Medicine Central DuPage Hospital in Winfield, ...



Harvard Business Review

What's Holding Women in Medicine Back from Leadership
Harvard Business Review
Reasons for gender disparities in the C-suite of medicine are manifold. For example, women do not achieve promotions or advancement to leadership positions at the same rate as their male peers. Highly qualified women do not attain independent grants, ...



MedPage Today

ADA Speakers Decry Gender Gap in Academic Medicine
MedPage Today
ORLANDO – Women remain less likely to reach the pinnacles of medical school academe than men, and their prospects haven't changed much in 30 years, researchers reported here at the annual scientific sessions of the American Diabetes Association.

and more »


MLive.com

Michigan Medicine reports $103 million surplus for 2018
MLive.com
ANN ARBOR, MI - Michigan Medicine reported a 2.4 percent operating margin for the 2018 fiscal year during its annual budget report on Thursday, June 21, resulting in a $103 million surplus from nearly $4.3 billion in revenue. Michigan Medicine also ...

and more »

Google News

home | site map | Dr. Thad Thomas
© 2006